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KMID : 0378019880310030099
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New Medical Journal
1988 Volume.31 No. 3 p.99 ~ p.103
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A Clinical Evaluation of Netilmicin in Severe Pulmonary Infections
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송시영/Song, Sie Young
윤어운/장준/김성규/이원영/Yoon, Yio Woon/Chang, Joon/Kim, Sung Kyu/Lee, Won Young
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Abstract
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A clinical study to evaluate the efficacy and safety of Netilmicin was performed in 18 patients with relatively severe pulmonary infectous diseases -including 3 cases of simple pneumonia. In 13 patients arr ong total 18 patients, the ´underlying diseases were 6 of lung cancer, 5 of COPD. and 2 of bronchiectesis:.
Patients were 21 to 76 years of age (average: 52 years) and 8 patients of total 18 patients were c ver 60 years old.
100mg or 150mg of Netilmicin twice daily was administered for 7 to 20 days.
The overall clinical response rate was 72% (13 cases) among 18 total cases: 8 cured, 5 improved and 2 cases were not evaluable. With respect to bacteriological results, 8 among 9 Gram(-) strains including Pseudomonas and Klebsiella isolated from sputum cultures were eliminated (88.9%). All patients were very well tolerated to Netilmicin with no complications or remarkable adverse reactions ever- in old aged group.
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